Fluoresceination of FepA during colicin B killing: effects of temperature, toxin and TonB

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Fluoresceination of FepA during colicin B killing: effects of temperature, toxin and TonB.

We studied the reactivity of 35 genetically engineered Cys sulphydryl groups at different locations in Escherichia coli FepA. Modification of surface loop residues by fluorescein maleimide (FM) was strongly temperature-dependent in vivo, whereas reactivity at other sites was much less affected. Control reactions with bovine serum albumin showed that the temperature dependence of loop residue re...

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ژورنال

عنوان ژورنال: Molecular Microbiology

سال: 2009

ISSN: 0950-382X,1365-2958

DOI: 10.1111/j.1365-2958.2009.06715.x